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Full Name and Degrees: 
Stella Chou, M.D.
Member Role: 
Lead Principal Investigator
Institutional affiliation: 
The Children's Hospital of Philadelphia

Stella T. Chou, M.D., is an attending physician in the Division of Hematology and the Apheresis Program at The Children's Hospital of Philadelphia.

Areas of Expertise: General pediatric hematology, Transfusion medicine, Sickle cell disease and alloimmunization, Apheresis


Stella Chou Laboratory

Led by Stella Chou, M.D., researchers in the Chou Laboratory are studying the molecular mechanisms of leukemia and other hematologic abnormalities in children with Down syndrome.

The long-term goal of this laboratory is to understand the contribution of trisomy 21 to the predisposition of children with Down syndrome to develop two related leukemias; transient myeloproliferative disease (TMD) and acute megakaryoblastic leukemia (AMKL).

Recent publications: 
Rh alloimmunization in chronically transfused patients with thalassemia receiving RhD, C, E, and K matched transfusions. Waldis SJ, Uter S, Kavitsky D, Flickinger C, Vege S, Friedman DF, Westhoff CM, Chou ST.Blood Adv. 2021 Feb 9;5(3):737-744. doi: 10.1182/bloodadvances.2020003732.PMID: 33560383 Transfusion and Cellular Therapy in Pediatric Sickle Cell Disease. Zheng Y, Chou ST.Clin Lab Med. 2021 Mar;41(1):101-119. doi: 10.1016/j.cll.2020.10.007. Epub 2020 Dec 24.PMID: 33494879 VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. Seu KG, Trump LR, Emberesh S, Lorsbach RB, Johnson C, Meznarich J, Underhill HR, Chou ST, Sakthivel H, Nassar NN, Seu KJ, Blanc L, Zhang W, Lutzko CM, Kalfa TA.Am J Hum Genet. 2020 Dec 3;107(6):1149-1156. doi: 10.1016/j.ajhg.2020.10.013. Epub 2020 Nov 12.PMID: 33186543
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