hiPSC Course at the Center for Regenerative Medicine (Boston)

The Center for Regenerative Medicine (CReM) at Boston University Medical Center is offering a five-day course that will focus on deriving, maintaining, characterizing and differentiating human induced pluripotent stem cells (hiPSCs). Small class size will enable researchers to learn the entire process of reprogramming from somatic cell preparation, to reprogramming methodologies, iPSC identification, isolation and characterization, and current approaches to their directed differentiation into endodermal and lung lineages.

Regenerative Medicine Funding Opportunity Announcements

NIH has developed a recorded Webinar to assist applicants to the 2018 Funding Opportunity Announcements for the Regenerative Medicine Innovation Project (RMIP) with preparing the most responsive applications possible.

MyoSeeds Research Grants Program (MyoKardia)

The MyoSeeds Research Grants Program will support research focused on basic biology of the heart and cardiomyopathies. Priority research areas for funding will be announced prior to each cycle. Priorities for the 2018-2019 Funding Cycle are focused on hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM).

Pre-application letters of intent are due by October 14, 2018, and grant selection notification and awards will occur no later than December 31, 2018.

PCTC “Jump-Start” Awards

PCTC Jump Start Award Program

Purpose:

To provide the PCTC with a mechanism to quickly award small grants to junior faculty (less than 5 years from their appointment to Assistant Professor), Research Associates, Graduate Students, Fellows and Postdocs to support a well-defined specific aim. The aim should involve at least one of the following, with priority given to proposals that incorporate two:

1.     The application of new technology to an existing translational research question

2nd Annual PCTC Meeting, September 27-28, 2018

2nd Annual PCTC Meeting

Online registration for the 2nd Annual NHLBI Progenitor Cell Translational Consortium (PCTC) Meeting in New York, NY (Thursday, September 27, 2018 and Friday, September 28, 2018) is now closed. We require a picture and brief description of your work for registration. These will be placed in the electronic booklet published on the PCTC website so colleagues with similar interests can identify you.

Long-term Contractile Activity and Thyroid Hormone Supplementation Produce Engineered Rat Myocardium with Adult-Like Structure and Function - Research Hub 07

Drs. Bursac, Jackman and Li show that a combination of low-rate (0.2 Hz) contractile activity and thyroid hormone (T3) supplementation significantly promote structural and functional maturation of engineered rat cardiac tissues (cardiobundles). [04Aug2018 Acta Biomater]

Read more:

Long-term Contractile Activity and Thyroid Hormone Supplementation Produce Engineered Rat Myocardium with Adult-Like Structure and Function

C. Jackman, H. Li, N. Bursac

“Effective Metabolic Approaches for the Energy Starved Failing Heart” – Zhang (UAB) Research Hub 07

Drs. Jianyi Zhang and E. Dale discuss ATP generation and utilization in the energy starved, failing heart. [19Jul2018 Circulation Research: VIEWPOINTS]

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Effective Metabolic Approaches for the Energy Starved Failing Heart

Bioenergetic Resiliency via Redundancy or Something Else?

Jianyi Zhang, E. Dale Abel

“Dissociation, Cellular Isolation and Initial Molecular Characterization of Neonatal and Pediatric Human Lung Tissues”

Drs. Gautam Bandyopadhyay, Heidie Huyck, Ravi Misra, Jeffrey Whitsett, and colleagues report novel methods that simultaneously isolate four major pulmonary cell populations from pediatric human lung. [05Jul2018 American Journal of Physiology - Lung Cellular and Molecular Physiology]

 

Read More:

Dissociation, Cellular Isolation and Initial Molecular Characterization of Neonatal and Pediatric Human Lung Tissues

 

Can We Engineer a Human Cardiac Patch for Therapy?

Drs. Jianyi Zhang, Wuqiang Zhu, Milica Radisic, and Gordana Vunjak-Novakovic provide a compendium of state-of-the-art developments in the fields of cardiovascular tissue engineering and challenges associated with their clinical use. [05Jul2018 Circulation Research: Regenerative Cardiology Compendium]

 

Read More:

Can We Engineer a Human Cardiac Patch for Therapy?”

 

Jianyi Zhang, Wuqiang Zhu, Milica Radisic, and Gordana Vunjak-Novakovic

GATA6 Suppression Enhances Lung Specification from Human Pluripotent Stem Cells

Drs. Chia-Min Liao, Somdutta Mukherjee, and colleagues reported that modulating GATA6 expression enhances the production of lung progenitors from human stem cell sources. [11Jun2018 JCI The Journal of Clinical Investigation]

Read more:

GATA6 Suppression Enhances Lung Specification from Human Pluripotent Stem Cells

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