Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28
posted by sitemanager
on Fri, 11/09/2018 - 11:30am
Research hub:
Publication Type:
Original Research Article
Name of Journal, Book, etc.:
Cell Reports
Year:
2018
PMID Reference:
Drs. Longfei Wang, R. Grant Rowe, George Daley, and colleagues report on the selective pharmacologic inhibition of individual domains of LIN28 and provide a foundation for therapeutic inhibition of the let-7 biogenesis pathway in LIN28-driven diseases. [05June2018 Cell Reports]
Copyright ©2016 NHLBI Progenitor Cell Translational Consortium.
