NOTCH Signaling Specifies Arterial-Type Definitive Hemogenic Endothelium from Human Pluripotent Stem Cells

posted by sitemanager on Tue, 05/15/2018 - 12:36pm
Research hub: 
Slukvin (UW-M) Research Hub 05
Author(s): 
Gene I. Uenishi, Ho Sun Jung, Akhilesh Kumar, Mi Ae Park, Brandon K. Hadland, Ethan McLeod, Matthew Raymond, Oleg Moskvin, Catherine E. Zimmerman, Derek J. Theisen, Scott Swanson, Owen J. Tamplin, Leonard I. Zon, James A. Thomson, Irwin D. Bernstein & Igor I. Slukvin
Publication Type: 
Original Research Article
Name of Journal, Book, etc.: 
Nature Communications
Year: 
2018
PMID Reference: 
Article

Drs. Gene Uenishi, Leonard Zon, James Thomson, and colleagues reported that NOTCH signaling is essential for arterial specification of hemogenic endothelium (HE) from hPSCs. [08May2018 Nature Communications]

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