A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development

posted by sitemanager on Fri, 11/09/2018 - 11:03am
Research hub: 
Daley (BCH) Research Hub 03
Author(s): 
Marcella Cesana, Michael Guo, Davide Cacchiarelli, Lara Wahlster, Jessica Barragan, Sergei Doulatov, Linda T. Vo, Beatrice Salvatori, Cole Trapnell, Kendell Clement, Patrick Cahan, Kaloyan M. Tsanov, Patricia M. Sousa, Barbara Tazon-Vega, Adriano Bolondi, Federico M. Giorgi, Andrea Califano, John L. Rinn, Alexander Meissner, Joel N. Hirschhorn, George Q. Daley
Publication Type: 
Original Research Article
Name of Journal, Book, etc.: 
Cell Stem Cell
Year: 
2018
PMID Reference: 
A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development

Drs. George Daley, Marcella Cesana, Michael Guo, and colleagues reported that hematopoietic stem cells (HSCs) manifest distinct alternative splicing patterns in key hematopoietic regulators. [05Apri2018 Cell Stem Cell]

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