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Autophagy: It's in Your Blood.

Author(s): 
Doulatov S, Daley GQ
Publication Type: 
Original Research Article
Name of Journal, Book, etc.: 
Dev Cell
Year: 
2017

 

Abstract

Autophagy, a central pathway for cellular homeostasis, plays diverse roles in development, cancer, aging, and neurodegeneration. In a new report in Nature, Ho et al. (2017) show that autophagy is essential for maintaining the replicative quiescence of hematopoietic stem cells throughout life by limiting the number of active mitochondria.

Copyright ©2016 NHLBI Progenitor Cell Translational Consortium.

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