“Cardiopatch Platform Enables Maturation and Scale-up of Human Pluripotent Stem Cell-derived Engineered Heart Tissues”

Drs. Nenad Bursac, Ilya Shadrin, Brian Allen, and colleagues report on a “Cardiopatch” platform for 3D culture and maturation of hiPSC-CMs (after 5 weeks of differentiation) showing robust electromechanical coupling, consistent H-zones, I-bands, and evidence for T-tubules and M-bands. [28Nov2017 Nature Communications]

Link to full article:

https://www.nature.com/articles/s41467-017-01946-x

 

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