PCTC Publications
| Title | Author(s) | Research hub |
|---|---|---|
| Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration | Kathiriya JJ, Brumwell AN, Jackson JR, Tang X, Chapman HA. | Chapman (UCSF) Research Hub 01 |
| Generation of multipotent induced cardiac progenitor cells from mouse fibroblasts and potency testing in ex vivo mouse embryos | Timothy Kamp, Pratik Lalit, Adriana Rodriguez, and Karen Downs | Zhang (UAB) Research Hub 07 |
| Autophagy: It's in Your Blood. | Doulatov S, Daley GQ | Daley (BCH) Research Hub 03 |
| Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis | Chapman HA, Wei Y, Montas G, Leong D, Golden JA, Trinh BN et al. | Chapman (UCSF) Research Hub 01 |
| Persistent Pathology in Influenza-Infected Mouse Lungs. | Kanegai CM, Xi Y, Donne ML, Gotts JE, Driver IH, Amidzic G, Lechner AJ, Jones KD, Vaughan AE, Chapman HA, Rock JR. Am J | Chapman (UCSF) Research Hub 01 |
| 2016 proceedings of the National Heart, Lung, and Blood Institute's scientific priorities in pediatric transfusion medicine. | Cure P, Bembea M, Chou S, Doctor A, Eder A, Hendrickson J, Josephson CD, Mast AE, Savage W, Sola-Visner M, Spinella P, Stanworth S, Steiner M, Mondoro T, Zou S, Levy C, Waclawiw M, El Kassar N, Glynn S, Luban NL. | Chou (CHOP) Research Hub 02 |
| Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal. | Adams WC, Chen YH, Kratchmarov R, Yen B, Nish SA, Lin WW, Rothman NJ, Luchsinger LL, Klein U, Busslinger M, Rathmell JC, Snoeck HW, Reiner SL. | Snoeck (CUMC) Research Hub 04 |
| A three-dimensional model of human lung development and disease from pluripotent stem cells | Ya-Wen Chen, Sarah Xuelian Huang, Ana Luisa Rodrigues Toste de Carvalho, Siu-Hong Ho, Mohammad Naimul Islam, Stefano Volpi, Luigi D. Notarangelo, Michael Ciancanelli, Jean-Laurent Casanova, Jahar Bhattacharya, Alice F. Liang, Laura M. Palermo, Matteo Porotto, Anne Moscona & Hans-Willem Snoeck | Snoeck (CUMC) Research Hub 04 |
| Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cells | Finn Hawkins,1,2 Philipp Kramer,3 Anjali Jacob,1,2 Ian Driver,4 Dylan C. Thomas,1 Katherine B. McCauley,1,2 Nicholas Skvir,1 Ana M. Crane,3 Anita A. Kurmann,1,5 Anthony N. Hollenberg,5 Sinead Nguyen,1 Brandon G. Wong,6 Ahmad S. Khalil,6,7 Sarah X.L. Huang,3,8 Susan Guttentag,9 Jason R. Rock,4 John M. Shannon,10 Brian R. Davis,3 and Darrell N. Kotton1,2 | Chapman (UCSF) Research Hub 01 |
| Specification and Diversification of Pericytes and Smooth Muscle Cells from Mesenchymoangioblasts | Akhilesh Kumar; Saritha Sandra D’Souza; Oleg V. Moskvin; Huishi Toh; Bowen Wang; Jue Zhang; Scott Swanson; Lian-Wang Guo; James A. Thomson; Igor I. Slukvin | Slukvin (UW-M) Research Hub 05 |
| Effective Metabolic Approaches for the Energy Starved Failing Heart | Jianyi Zhang, E. Dale Abel | Zhang (UAB) Research Hub 07 |
| Functional Characterization of Human Pluripotent Stem Cell-Derived Arterial Endothelial Cells | Jue Zhang, Li-Fang Chu, James Thomson | Slukvin (UW-M) Research Hub 05 |
| Dissociation, Cellular Isolation and Initial Molecular Characterization of Neonatal and Pediatric Human Lung Tissues | Gautam Bandyopadhyay, Heidie L. Huyck, Ravi S Misra, Soumyaroop Bhattacharya, Qian Wang, Jared Mereness, Jacquelyn Lillis, Jason R Myers, John Ashton, Timothy Bushnell, Matthew Cochran, Jeanne Holden-Wiltse, Philip Katzman, Gail Deutsch, Jeffrey Whitsett, Yan Xu, Thomas J. Mariani, Gloria S. Pryhuber | Whitsett (CCHMC) Research Hub 06 |
| Lung Gene Expression Analysis (LGEA): An Integrative Web Portal for Comprehensive Gene Expression Data Analysis in Lung Development | Yina Du1, Joseph A Kitzmiller1, Anusha Sridharan1, Anne K Perl1, James P Bridges1, Ravi S Misra4, Gloria S Pryhuber4, Thomas J Mariani4, Soumyaroop Bhattacharya4, Minzhe Guo1, S Steven Potter2, Phillip Dexheimer3, Bruce Aronow3, Alan H Jobe1, Jeffrey A Whitsett1, Yan Xu1,3 | Whitsett (CCHMC) Research Hub 06 |
| Activation of the Arterial Program Drives Development of Definitive Hemogenic Endothelium with Lymphoid Potential | Mi Ae Park, Akhilesh Kumar, Ho Sun Jung, Gene Uenishi, Oleg V. Moskvin, James A. Thomson, Igor I. Slukvin | Slukvin (UW-M) Research Hub 05 |
| SLICE: Determining Cell Differentiation and Lineage Based on Single Cell Entropy | Minzhe Guo, Erik Bao, Jeffrey Whitsett | Whitsett (CCHMC) Research Hub 06 |
| CCND2 Overexpression Enhances the Regenerative Potency of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Remuscularization of Injured Ventricle | ||
| Can We Engineer a Human Cardiac Patch for Therapy? | Jianyi Zhang, Wuqiang Zhu, Milica Radisic, and Gordana Vunjak-Novakovic | Zhang (UAB) Research Hub 07 |
| EMC3 Coordinates Surfactant Protein and Lipid Homeostasis Required for Respiration | ||
| Cardiopatch Platform Enables Maturation and Scale-up of Human Pluripotent Stem Cell-derived Engineered Heart Tissues | ||
| Neural Crest State Activation in NRAS Driven Melanoma, but not in NRAS-driven Melanocyte Expansion | Leonard Zon, Alicia McConnell, Jeffrey Mito | Daley (BCH) Research Hub 03 |
| GATA6 Suppression Enhances Lung Specification from Human Pluripotent Stem Cells | Chia-Min Liao,1,2 Somdutta Mukherjee,2 Amita Tiyaboonchai,2 Jean Ann Maguire,1,2 Fabian L. Cardenas-Diaz,1,2 Deborah L. French,1,2 and Paul Gadue1,2 | Chou (CHOP) Research Hub 02 |
| Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28 | Longfei Wang, R. Grant Rowe, George Daley | Daley (BCH) Research Hub 03 |
| Distinct Mesenchymal Lineages and Niches Promote Epithelial Self-Renewal and Myofibrogenesis in the Lung | ||
| Mutation-Specific Signaling Profiles and Kinase Inhibitor Sensitivities of Juvenile Myelomonocytic Leukemia Revealed by Induced Pluripotent Stem Cells | Sarah K. Tasian, Jessica A. Casas, Stella Chou | Chou (CHOP) Research Hub 02 |
| Sustained miRNA Delivery from an Injectable Hydrogel Promotes Cardiomyocyte Proliferation and Functional Regeneration after Ischaemic Injury | ||
| Dye-Independent Methods Reveal Elevated Mitochondrial Mass in Hematopoietic Stem Cells | Mariana Justino de Almeida , Larry L. Luchsinger , David J. Corrigan , Linda J. Williams , Hans-Willem Snoeck | Snoeck (CUMC) Research Hub 04 |
| Dye-Independent Methods Reveal Elevated Mitochondrial Mass in Hematopoietic Stem Cells | Mariana Justino de Almeida , Larry L. Luchsinger , David J. Corrigan , Linda J. Williams , Hans-Willem Snoeck | Snoeck (CUMC) Research Hub 04 |
| Large Cardiac-Muscle Patches Engineered from Human Induced-Pluripotent Stem-Cell–Derived Cardiac Cells Improve Recovery from Myocardial Infarction in Swine | Jianyi (Jay) Zhang, Ling Gao, Zachery Gregorich, Wuqiang Zhu, and colleagues | Zhang (UAB) Research Hub 07 |
| A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development | Marcella Cesana, Michael Guo, Davide Cacchiarelli, Lara Wahlster, Jessica Barragan, Sergei Doulatov, Linda T. Vo, Beatrice Salvatori, Cole Trapnell, Kendell Clement, Patrick Cahan, Kaloyan M. Tsanov, Patricia M. Sousa, Barbara Tazon-Vega, Adriano Bolondi, Federico M. Giorgi, Andrea Califano, John L. Rinn, Alexander Meissner, Joel N. Hirschhorn, George Q. Daley | Daley (BCH) Research Hub 03 |
| Regeneration of the Lung Alveolus by an Evolutionarily Conserved Epithelial Progenitor | ||
| Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium | ||
| A Humanized Mouse Model Generated Using Surplus Neonatal Tissue | Matthew Brown, Ying Zhou, James Thomson, et al | Slukvin (UW-M) Research Hub 05 |
| Cardiac Recovery via Extended Cell-Free Delivery of Extracellular Vesicles Secreted by Cardiomyocytes Derived from Induced Pluripotent Stem Cells | Bohao Liu, Benjamin W. Lee, Koki Nakanishi, Aranzazu Villasante, Rebecca Williamson, Jordan Metz, Jinho Kim, Mariko Kanai, Lynn Bi, Kristy Brown, Gilbert Di Paolo, Shunichi Homma, Peter A. Sims, Veli K. Topkara & Gordana Vunjak-Novakovic | Snoeck (CUMC) Research Hub 04 |
| Spatial-Temporal Lineage Restrictions of Embryonic p63+ Progenitors Establish Distinct Stem Cell Pools in Adult Airways | Y. Yang, P. Riccio, M. Schotsaert, M. Mori, J. Lu, D-K. Lee ,A. Garcıa-Sastre, J. Xu, and W.V. Cardoso. | Snoeck (CUMC) Research Hub 04 |
| Big Bottlenecks in Cardiovascular Tissue Engineering | Ngan F. Huang, Vahid Serpooshan, Viola B. Morris, Nazish Sayed, Gaspard Pardon, Oscar J. Abilez, Karina H. Nakayama, Beth L. Pruitt, Sean M. Wu, Young-sup Yoon, Jianyi Zhang & Joseph C. Wu | Zhang (UAB) Research Hub 07 |
| Advanced Maturation of Human Cardiac Tissue Grown From Pluripotent Stem Cells | Kacey Ronaldson-Bouchard, Stephen P. Ma, Keith Yeager, Timothy Chen, LouJin Song, Dario Sirabella, Kumi Morikawa, Diogo Teles, Masayuki Yazawa & Gordana Vunjak-Novakovic | Snoeck (CUMC) Research Hub 04 |
| NOTCH Signaling Specifies Arterial-Type Definitive Hemogenic Endothelium from Human Pluripotent Stem Cells | Gene I. Uenishi, Ho Sun Jung, Akhilesh Kumar, Mi Ae Park, Brandon K. Hadland, Ethan McLeod, Matthew Raymond, Oleg Moskvin, Catherine E. Zimmerman, Derek J. Theisen, Scott Swanson, Owen J. Tamplin, Leonard I. Zon, James A. Thomson, Irwin D. Bernstein & Igor I. Slukvin | Slukvin (UW-M) Research Hub 05 |
| Highly Efficient CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells | ||
| Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling | Katherine McCauley, Finn Hawkins, Darrell Kotton | |
| Human Leukocyte Antigen Class I and II Knockout Human Induced Pluripotent Stem Cell–Derived Cells: Universal Donor for Cell Therapy | Saidulu Mattapally, Kevin M. Pawlik, Vladimir G. Fast, Esther Zumaquero, Frances E. Lund, Troy D. Randall, Tim M. Townes, Jianyi Zhang | Zhang (UAB) Research Hub 07 |
| Transfusion and Cellular Therapy in Pediatric Sickle Cell Disease | Zheng Y, Chou ST | Chou (CHOP) Research Hub 02 |
| VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects | Seu KG, Trump LR, Emberesh S, Lorsbach RB, Johnson C, Meznarich J et al | Chou (CHOP) Research Hub 02 |
| YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow | Lundin V, Sugden WW, Theodore LN, Sousa PM, Han A, Chou S, et al. | Daley (BCH) Research Hub 03 |
| Calmodulin Inhibitors Improve Erythropoiesis in Diamond-Blackfan Anemia | Taylor AM, Macari ER, Chan IT, Blair MC, Doulatov S, Vo LT, et al. | Daley (BCH) Research Hub 03 |
| The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future | Basil MC, Katzen J, Engler AE, Guo M, Herriges MJ, Kathiriya JJ, et al. | Snoeck (CUMC) Research Hub 04 |
| Xenogeneic Cross-Circulation for Extracorporeal Recovery of Injured Human Lungs | Hozain AE, O'Neill JD, Pinezich MR, Tipograf Y, Donocoff R, Cunningham KM, et al. | Snoeck (CUMC) Research Hub 04 |
| Biologically Functionalized Expanded Polytetrafluoroethylene Blood Vessel Grafts | Wang D, Xu Y, Lin YJ, Yilmaz G, Zhang J, Schmidt G, et al. | Slukvin (UW-M) Research Hub 05 |
| Reproducibility Across Single-cell RNA-seq Protocols for Spatial Ordering Analysis | Seirup M, Chu LF, Sengupta S, Leng N, Browder H, Kapadia K, et al. | Slukvin (UW-M) Research Hub 05 |
| Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis | Guo M, Yu JJ, Perl AK, Wikenheiser-Brokamp KA, Riccetti M, Zhang EY et al. | Whitsett (CCHMC) Research Hub 06 |
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